Important Billing Code Update for CPT Code 0449U

Date: 10/31/25

(Effective January 1, 2026)

Please Note:

CPT Code 0449U will no longer be a covered benefit as of January 1, 2026.

The breakdown of this code is as follows:

• This is a Proprietary Laboratory Analysis (PLA) code that is only utilized by one provider.
• Similar services are available through in-network labs, such as Quest and LabCorp.

If you have questions about this bulletin or other provider resources, please contact your Provider Relations Representative.